Cytohubba stress
WebJul 30, 2024 · Stress is a state of the body a non-specific response to any demand for change. Cancer had a deep relation with stress. Activation of the stress response and … WebcytoHubba. Predicts and explores important nodes and subnetworks in a given network by several topological algorithms. Categories: clustering, Connection sub-graph discovery, graph analysis, network …
Cytohubba stress
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Webfrom publication: cytoHubba: Identifying hub objects and sub-networks from complex interactome Background Network is a useful way for presenting many types of biological data including protein ... WebNov 26, 2024 · The target of RA was screened based on Comparative Toxicogenomics Database (CTD). The key genes were output by the four algorithms' maximum neighborhood component (MNC), degree, maximal clique centrality (MCC), and stress in cytoHubba in Cytoscape, while biological functions and pathways were also analyzed.
WebJan 4, 2024 · The Cytoscape plugin cytoHubba was applied to identify hub genes from the PPI network. Connectivity value and stress methods were used to identify hub genes. Significant clusters were generated by using PEWCC (version 1.0) . Significant transcription factors (TFs) were screened by generating the TF-gene network. Web 目的 运用生物信息学分析, 探讨硫利达嗪抗宫颈癌的潜在作用机制。 方法 通过PharmMapper工具预测能够与硫利达嗪相互作用的靶基因,然后使用STRING在线工具对靶基因进行通路和组织表达富集分析。使用GeneCards和DisGeNET数据库筛选宫颈癌相关基因,与硫利达嗪的靶基因取交集,得到硫利 ...
WebJul 30, 2024 · Stress is a state of the body a non-specific response to any demand for change. Cancer had a deep relation with stress. Activation of the stress response and exposure to the associated hormones could promote the growth and spread of tumors. The immune system can be important for finding and eliminating cancer cells. WebApr 1, 2024 · The extent of drought stress is varieties and time-dependent, however, the molecular response mechanisms of drought tolerance in sunflower with different varieties are still unclear. ... CytoHubba analysis showed that the top 10 genes all encoded ribosomal proteins. Up-regulated genes were enriched in the KEGG pathway of …
WebJan 1, 2024 · CytoNCA and cytoHubba were performed and identified overlapping DEGs. In addition, we narrowed down DEGs by filtering with immune-related genes and identified … microsoft word 2010 tutorialspoint pdfWebMar 4, 2024 · A plugin named cytoHubba was introduced to screen hub genes of PPI network in Cytoscape. CytoHubba can provide 12 topological analysis methods including Betweenness, BottleNeck, Closeness, Clustering Coefficient, Degree, DMNC, EcCentricity, EPC, MCC, MNC, Radiality and Stress based on shortest paths . Results. Normalization … microsoft word 2010 publisherWebNov 26, 2024 · The key genes were output by the four algorithms' maximum neighborhood component (MNC), degree, maximal clique centrality (MCC), and stress in cytoHubba … microsoft word 2010 restrict editingWebCytoHubba provides 11 topological analysis methods including Degree, Edge Percolated Component, Maximum Neighborhood Component, Density of Maximum Neighborhood Component, Maximal Clique Centrality and six centralities (Bottleneck, EcCentricity, Closeness, Radiality, Betweenness, and Stress) based on shortest paths. microsoft word 2010 tảiWebFeb 22, 2024 · We used algorithms of Cytohubba, molecular complex detection, Lasso logistic regression, and support vector machine to identify the key biomarkers. ... Cardiac myocytes have elevated levels of THBS1 in response to stress stimulation 15 and THBS1 can release active TGF-β and trigger fibrosis. 16 This trial demonstrates that THBS1 is … microsoft word 2010 technical supportWebApr 28, 2024 · 1、首先选择左边的 cytoHubba 进入工作页面 2、 Target Network 选择待分析的网络 3、点击 Calculate 4、点击 Top 10 ,可根据自身课题需要,调整提取关键基因的数量 5、下方 MCC 可下拉选择计算方法 6、 Particular nodes :选择感兴趣的基因进行分析(一般是对整个网络分析的话,此项可以忽略) 5、点击左下方 Display the shortest … microsoft word 2010 websiteWebMar 18, 2024 · The top 20 hub genes were calculated using the seven algorithms of the plug-in CytoHubba ... Closeness, Radiality, Stress, and EPC) were used in evaluating and selecting hub genes. microsoft word 2010 training manual