Soft text trials

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August undefined, 2024

WebApr 20, 2024 · Purpose: The Tamoxifen and Exemestane Trial (TEXT)/Suppression of Ovarian Function Trial (SOFT) showed superior outcomes for premenopausal women with … WebMar 30, 2024 · Enrollment in the TEXT and SOFT trials. (A) TEXT: Between November 2003 and April 2011, TEXT enrolled 2672 patients; enrollment was suspended 1 December 2007 and re-opened by protocol amendment released in July 2008, with enrollment restarted in December 2008.

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WebFeb 16, 2024 · In 2013, two randomized trials were initiated by the International Breast Cancer Study Group: The Suppression of Ovarian Function Trial (SOFT) and the … WebMar 30, 2024 · Enrollment in the TEXT and SOFT trials. (A) TEXT: Between November 2003 and April 2011, TEXT enrolled 2672 patients; enrollment was suspended 1 December … how long can coconut last

Surgical ovarian suppression for adjuvant treatment in hormone receptor …

WebMeredith M. Regan, ScD, Harvard Medical School, Boston, MA, gives an update on the 12-year follow-up results of the SOFT (NCT00066690) and TEXT (NCT00066703)... WebSOFT and TEXT are phase III clinical trials developed in parallel to test the optimal post-operative (i.e. adjuvant) endocrine treatment in premenopausal women with hormone … how long can coffee beans last

JNCCN 360 - Breast - SABCS 2024: Can Patients With Hormone …

WebDec 16, 2024 · Secondary analysis of SOFT and TEXT trials results in development of a risk score to guide decision making in adjuvant endocrine therapy for premenopausal women … WebDec 9, 2024 · Trial participants were strongly recommended to resume endocrine therapy after a pregnancy attempt or success. To date, 76.3 percent have resumed their therapy, the authors said. Partridge and Pagani said the study provides encouraging guidance to younger women diagnosed with breast cancer who may be hoping to have children. how long can cocaine be detectedWebApr 7, 2024 · Peri-Implant Soft Tissue Integration in Humans: Influence of Material The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by … how long can cockatiels live in captivity

"http://research.bigagainstbreastcancer.org/clinical-trials/soft-text-big-2-02-big-3-02 " - Soft text trials

Soft text trials

Tailoring Adjuvant Endocrine Therapy for Premenopausal …

WebThe landscape of adjuvant endocrine therapy in premenopausal women has changed significantly since the joint analysis of the SOFT and TEXT trials.7 These data had a median follow-up of 8 years, with findings suggesting an overall survival benefit of 1.8% for women receiving tamoxifen plus ovarian suppression versus tamoxifen alone (HR 0.59; 95% ... WebDec 21, 2024 · The phase 3 trial (ClinicalTrials.gov Identifier: NCT03155997) included 5637 patients with HR-positive, HER2-negative, node-positive, high-risk early breast cancer.

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WebJun 4, 2024 · The trial designs and eligibility criteria in SOFT and TEXT have been described previously. 6-8 The two trials included women with documented premenopausal status … WebJul 25, 2024 · The 8-year overall survival of these women in the SOFT trial was 98.8% for tamoxifen, 97.9% for tamoxifen plus ovarian function suppression, and 97.7% for …

WebAug 7, 2003 · Patient-reported outcomes with adjuvant exemestane versus tamoxifen in premenopausal women with early breast cancer undergoing ovarian suppression (TEXT … WebDec 17, 2024 · Over all four trials, median follow-up was 8.0 years. In the ABCSG-12 trial 5% of patients received neoadjuvant chemotherapy. In TEXT, 60% of patients received …

WebFeb 28, 2024 · Knowing the material properties of the musculoskeletal soft tissue could be important to develop rehabilitation therapy and surgical procedures. However, there is a lack of devices and information on the viscoelastic properties of soft tissues around the lumbar spine. The goal of this study was to develop a portable quantifying device for providing … WebSep 27, 2024 · Several trials evaluated the role of ovarian function suppression for the adjuvant treatment of premenopausal patients with hormone receptor-positive early breast cancer. Based on the results of the SOFT and TEXT trials, international guidelines recommend the addition of ovarian function suppression to standard adjuvant endocrine …

WebApr 7, 2024 · Malakoplakia is a rare condition characterized by inflammatory masses with specific histological characteristics. These soft tissue masses can mimic tumors and tend to develop in association with chronic or recurrent infections, typically of the urinary tract. A specific defect in innate immunity has been described. In the absence of randomized …

http://research.bigagainstbreastcancer.org/soft-text how long can cockroaches go without foodWebMar 10, 2024 · The benefits of ovarian function suppression were sustained long term for premenopausal women with hormone receptor–positive breast cancer, according to … how long can constipation last in teensWebDec 11, 2014 · In 2003, the International Breast Cancer Study Group (IBCSG) initiated two randomized, phase 3 trials, the Suppression of Ovarian Function Trial (SOFT) and the … how long can concrete stay in a pump truckWebApr 14, 2024 · After primary treatment with curative intent for soft tissue sarcoma, patients fulfilling the inclusion criteria and giving informed consent are enrolled. In study protocol patients have their regular chest x-ray once in two months plus ultra-low-dose computed tomography imaging is repeated seven times during the first two years of follow-up. how long can cockroach survive without headWebMar 21, 2024 · Promising results were also reported from the POSITIVE trial in women (<42y), where ET was interrupted to allow for pregnancy. The primary outcome of BC-free … how long can coffee mate creamer sit outWebDec 15, 2012 · Background: The SOFT and TEXT randomized phase 3 trials address two primary questions for endocrine treatment of premenopausal women with hormone … how long can constipation pain lastWebThe results obtained in the Bifocal Lenses in Nearsighted Kids (BLINK) trial of Biofinity center-distance multifocal soft contact lenses were similar to those of MiSight lenses, based on a broad overlap of the 95% confidence intervals (CI) for their primary outcomes. 17,18,25 The BLINK trial tested Biofinity center-distance multifocal contact lenses (+1.50 D and … how long can coconut milk be refrigerated